Investors have all eyes fixed on the Federal Reserve’s annual economic symposium in Jackson Hole, Wyo., as the Fed charts the future direction of the monetary policy in what could be a defining moment for the market’s summer story.

Powell's speech at Jackson Hole will set the tone for policy through the rest of this year. BofA says the speech will drive big swings in these stocks.

The S&P 500 extended its losing streak Thursday, with investors cautious ahead of Jerome Powell's Jackson Hole speech on Friday.