Week 17 is also loaded with playoff implications. Teams like the Houston Texans (10-5), Los Angeles Chargers (11-4), Chicago Bears (11-4) and San Francisco 49ers (11-4) are still vying for higher seeds in the AFC and NFC.

Each pick has a confidence level of 1-10, with 10 being the most confident. For more information on the pick methodology, check out the Week 1 edition of this series. Keep in mind that since the idea here is to make high-percentage plays,

Both the Dallas Cowboys (6-8-1) and the Washington Commanders (4-11) are playing out the string the last two weeks of the 2025 season. The two NFC East rivals are both eliminated from postseason contention,

Denver clinches the West with a win against the Chiefs and a Chargers loss to the Texans. Mike Florio and Chris Simms thinks things could get ugly in Kansas City during Week 17 with what should be an angry Broncos team.