Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...

Our cells are usually frantically working to sustain life. Part of this work includes dividing, a process that creates more cells to support our growth when we are children or to replace old, worn-out ...

Emerging evidence highlights that epigenetic alterations—including DNA methylation, histone modification, and chromatin ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, determines which genetic instructions are activated. When this fails, the wrong ...

New in vitro results show Telomir-1 adds KDM5 family inhibition to its previously reported KDM2/KDM6 and DNA methylation ...

For the first time, Chinese scientists have fully revealed how a single plant somatic cell develops into a complete plant.

EZH2, the catalytic core of the Polycomb Repressive Complex 2 (PRC2), silences gene expression through H3K27me3 modification and is emerging as a master epigenetic regulator beyond cancer. The review ...

Telomir Pharmaceuticals (TELO) announced new in vitro pharmacology results demonstrating that Telomir-1 potently inhibits three members of the ...

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold ...