The human liver plays a pivotal role in drug metabolism, largely attributable to the diverse family of UDP-glucuronosyltransferases (UGTs) that catalyse glucuronidation reactions. This conjugation ...

Liver disease is the new “silent killer” that’s quietly becoming one of the world’s biggest health concerns. The most common type among different kinds of liver diseases, fatty liver disease, is ...

The liver is accountable for metabolizing most medications and is therefore one of the primary tissues affected by adverse drug reactions. Most classes of medicine can cause drug-induced liver injury ...

Founded by Flagship Pioneering in 2019, Cellarity seeks to embrace biology’s complexity, as diseases are often not driven by a single target, but emerge from a cascade of cellular interactions that ...

Three-dimensional multicellular human liver model: For the first time, a 3D human organoid model, developed with liver tissue ...

Tremfya (guselkumab) has potential interactions with certain other medications, such as abatacept (Orencia) and paroxetine (Brisdelle, Paxil). Using Tremfya may also affect how your body responds to ...

By recreating a fetal liver niche, FLOs show how liver and immune cells co-develop. Learn more about new groundbreaking ...

The FDA granted accelerated approval to oral elafibranor (Iqirvo) for treating primary biliary cholangitis (PBC) in adults, drugmaker Ipsen announced on Monday. A first-in-class dual peroxisome ...