Adrenergic drugs are medications that stimulate certain nerves in your body. They do this either by mimicking the action of the chemical messengers epinephrine and norepinephrine or by stimulating ...

Noradrenaline is a neuromodulator secreted in the brain depending on behavioral context and physiological states of animal, influencing a wide range of physiological functions by modulating brain ...

Beta-adrenergic signaling mechanisms are of central importance to cardiovascular health and disease. Modulation of these pathways represents an important pharmacologic approach to the treatment of ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 70, No. 8 (1973), pp. 2411-2414 (4 pages) Depletion of neural norepinephrine by reserpine treatment or by ...

Sept. 8, 2003 — Beta-adrenergic receptors and angiotensin II type 1 receptors join to form receptor complexes, allowing single antagonist drugs used to treat heart failure to have a dual effect, ...

Fully understanding the mechanisms of signaling proteins such as G protein-coupled receptors (GPCRs) will require the characterization of their conformational states and the pathways connecting those ...

Recent clinical studies have suggested that phenylacetylglutamine (PAGln), a novel gut microbial metabolite, can mechanistically modulate patients' risk of developing cardiovascular disease (CVD) and ...