The tissue phase plasmodium enters into the Red cells and develops into a trophozoite. From the trophozoite numerous merozoites are liberated into the blood stream. Each merozoite liberated attacks ...

Extrusion of chloroquine (CQ) from digestive vacuoles through the Plasmodium falciparum CQ resistance transporter (PfCRT) is essential to establish CQ resistance of the malaria parasite. However, the ...

Calcium is essential for the correct functioning of the cell and requires regulation to avoid high concentrations causing cell death. Calcium ions are important for cell signaling as the binding of ...

The role of molecular chaperones, among them heat shock proteins (Hsps), in the development of malaria parasites has been well documented. Hsp70s are molecular chaperones that facilitate protein ...

A new, comprehensive map of all the genes essential for blood infections in Plasmodium knowlesi (P. knowlesi), a parasite ...

The development and implementation of a malaria vaccine would constitute a major breakthrough for global health. Recently, numerous new candidates have entered clinical testing, following strategies ...

The evolutionary path of the deadliest human malaria parasite, Plasmodium falciparum, has been revealed for the first time. This parasite is a member of the Laverania parasite family that only infect ...

High-flying mosquitoes in West Africa are carriers of multiple pathogens, including West Nile virus, highlighting risks in ...

When a person is bitten by an infected female Anopheles mosquito, sporozoites of malarial parasites are injected into the blood stream. Inside the blood, the sporozoites circulate before entering the ...

Plasmodium Ovale is not a very common type of malaria that has been identified in a soldier in Kerala who is believed to have contracted in Sudan during his posting, where Plasmodium Ovale is endemic.