DNA replication is a basic function of living organisms, allowing cells to divide and multiply, all while maintaining the genetic code and proper function of the original cell. The process, or ...

The manipulation of DNA replication and the adoption of advanced gene-editing technologies illustrate a remarkable convergence of scientific innovation and ethical considerations.

Almost all life on earth is based on DNA being copied, or replicated, and understanding how this process works could lead to a wide range of discoveries in biology and medicine. Now for the first time ...

During S-phase, DNA replication takes place in five stages. They are: initiation, unwinding, primer synthesis, elongation, and termination. Helicase enzymes “unwind” the DNA double helix, and ...

Figure 1: Primer synthesis occurs concomitantly with DNA unwinding and synthesis. Figure 2: Priming loop: the primase domain maintains contact with the priming sequence during replication. Making ...

DNA Replication: Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism.

Accurate transmission of the genetic information requires complete duplication of the chromosomal DNA each cell division cycle. However, the idea that replication forks would form at origins of DNA ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes ...

Research groups also have found that immobilizing strands of DNA helps DNA replication. So, Christopher Deck and his colleagues decided to apply immobilization on RNA replication.

Researchers at the University of California, Davis, have just reported a small but significant accomplishment: catching the replication of a single DNA molecule on video for the first time. And ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.