Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig's disease, is an incurable neurological disorder affecting motor ...

Dampening the integrated stress response (IRS) in motor neurons may be a valid therapeutic approach in patients with an inherited form of ALS.

CLEVELAND— Amyotrophic lateral sclerosis (ALS ), known as Lou Gehrig's disease, is an incurable neurological disorder affecting motor neurons—nerve ...

Far-field potentials (FFPs), nerve signals that can be measured on the skin, show promise as diagnostic and prognostic ...

Apathy and depression are the most prevalent neuropsychiatric symptoms in amyotrophic lateral sclerosis (ALS).1-3 Although ...

Converging evidence supports a key pathogenic role of the glymphatic system in the accumulation of pathological aggregates in ...

Study shows how ALS-linked mutations disrupt the protein TDP-43 at the atomic level, preventing it from executing its ...

Medically reviewed by Nicholas R. Metrus, MD Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a progressive neurodegenerative disease. It affects your nerves and muscle tissue and ...