NFL Football Picks Week 9 Lines

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NFL Week 1 picks and predictions, straight-up and ATS

Computer model unveils NFL against the spread, over/under, money-line picks for every Week 1 game

The 2025 NFL regular season kicks off on Thursday, with the defending Super Bowl champion Philadelphia Eagles (-8.5) hosting the Dallas Cowboys in the 2025 NFL Kickoff Game.

Niners Wire · 5d

Panthers vs Jaguars picks, predictions, odds: Who wins NFL Week 1 game?

Badgers Wire · 5d

49ers vs Seahawks picks, predictions, odds: Who wins NFL Week 1 game?

· 1d

Is there a Monday Night Football game tonight? NFL Week 1 schedule

The opening game of the 2025 NFL season is slated for Thursday, Sept. 4 from Lincoln Financial Field in Philadelphia.

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NFL Week 1 predictions: ESPN matchup predictor's picks, win probabilities for this week

· 13h

Ranking the 10 Best NFL Offenses in Week 1 of 2025 Season, Including the Commanders & Chiefs

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Week 1 NFL odds, lines, top betting picks, spreads, best bets, 2025 predictions: Model likes Packers, Bengals

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks its since inception.

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What NFL games are this week? NFL Week 1 TV schedule

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Lions vs. Packers bold predictions for Week 1 of 2025 NFL season

NFL parlays: Best bets, picks, updated odds for 2025 season

Find the best NFL parlays for the 2025-26 season. Learn how NFL parlays work, when to use them, where to bet on them and the top bonus offers available.

40mon MSN

2025 NFL Week 1 Odds Specials: Will Burrow, Barkley Shine to Begin the Season?

Which team will score most? How many total TDs across the league? Which game will be the lowest scoring? Check out all the ways to bet NFL Week 1.