BMJ

Effects of vitamin D supplementation on cognitive function and blood Aβ-related biomarkers in older adults with Alzheimer’s disease: a randomised, double-blind, placebo ...

1 Department of Epidemiology and Biostatistics, School of Public Health,Tianjin Medical University, Tianjin, China 2 Department of Infectious Diseases, Tianjin Medical University General Hospital, ...
BMJ

Time course of wallerian degeneration after ischaemic stroke revealed by diffusion tensor imaging

Neuroimage Nord, Klinik und Poliklinik für Neurologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany Correspondence to: G Thomalla Klinik und Poliklinik für Neurologie, Universitätsklinikum ...
BMJ

Comparison between the lumbar infusion and CSF tap tests to predict outcome after shunt surgery in suspected normal pressure hydrocephalus

Correspondence to: Dr S Rehncrona, Department of Neurosurgery, University Hospital, S-221 85 Lund, Sweden; stig.rehncrona{at}neurokir.lu.se Objective: To compare the lumbar infusion test and the ...
BMJ

Do medically unexplained symptoms matter? A prospective cohort study of 300 new referrals to neurology outpatient clinics

Dr A J Carson. Department of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF. emailA.Carson{at}ed.ac.uk METHODS The prospective cohort study with ...
BMJ

Anti-Aβ agents for mild to moderate Alzheimer's disease: systematic review and meta-analysis

Methods The MEDLINE, Embase, Cochrane Central Register of Controlled Trials, PsycINFO, ClinicalTrials.gov and the WHO’s International Clinical Trials Registry Platform search portal were searched from ...
BMJ

Intraoperative microvascular Doppler ultrasonography in cerebral aneurysm surgery

a Department of Neurosurgery, Benjamin Franklin Medical Center, Free University of Berlin, Hindenburgdamm 30, 12200 Berlin, Germany, b Department of Radiology Dr Ruediger Stendel, Department of ...
BMJ

The 39 item Parkinson’s disease questionnaire (PDQ-39) revisited: implications for evidence based medicine

Background: The 39 item Parkinson’s disease questionnaire (PDQ-39) is the most widely used patient reported rating scale in Parkinson’s disease. However, several fundamental measurement assumptions ...
BMJ

I02 Systemic injection of exosomal sirna significantly reduced huntingtin expression in transgenic mice of huntington’s disease

Background Cell-derived exosomes have been demonstrated to be efficient carriers of small RNAs into brain tissue. However, the therapeutic effect of exosome-mediated siRNA has not been tested in ...
BMJ

Neurophysiological predictors of long term response to AChE inhibitors in AD patients

Background: In vivo evaluation of cholinergic circuits of the human brain has recently been introduced using a transcranial magnetic stimulation (TMS) protocol based on coupling peripheral nerve ...
BMJ

The United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: final results.

From 1979-85, 2435 patients with a transient ischaemic attack or minor ischaemic stroke were randomly allocated to receive long term "blind" treatment with aspirin 600 mg twice daily (n = 815), ...
BMJ

Comparison of elevated phosphorylated neurofilament heavy chains in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis

Correspondence to Professor Koen Poesen, Department of Neurosciences, Laboratory for Molecular Neurobiomarker Research, KU Leuven (University of Leuven), 3000 Leuven, Belgium; ...
BMJ

Measuring change in disability after inpatient rehabilitation: comparison of the responsiveness of the Barthel Index and the Functional Independence Measure

Professor AJ Thompson, Institute of Neurology, Queen Square, London WC1N 3BG, UK. Telephone 0044 171 837 3611 ext 4152; fax 0044 171 813 6505; email athompson{at}ion.ucl.ac.uk BACKGROUND The ...