The Rome diagnostic criteria for the functional bowel disorders and functional abdominal pain are used widely in research and practice. A committee consensus approach, including criticism from ...

Background—Barrett’s oesophagus is acquired by severe gastro-oesophageal reflux and is a premalignant condition. Acid suppression or anti-reflux surgery alone do not cause significant regression of ...

1 Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands 2 Department of Surgery, Academic Medical Center Amsterdam, Amsterdam, The Netherlands 3 Department of Surgery, ...

Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea Correspondence to Professor Young-Suk Lim, Department of ...

2 Department of Transplant Surgery, Addenbrooke’s Hospital, Cambridge, UK Correspondence to: Dr S J Middleton Unit E7, Department of Gastroenterology, Addenbrooke’s Hospital, Hills Rd, Cambridge CB2 ...

Background and aims: The incidence of gastric cancer in Japan is four times higher than in the UK. It usually arises in a stomach with corpus predominant or pangastritis that has undergone extensive ...

Objective Longitudinal evidence is lacking regarding the long-term risk of major adverse cardiovascular events (MACE) in children and young adults with non-alcoholic fatty liver disease (NAFLD).

Background The polarization of M1 macrophage facilitates steatotic liver graft injury and is regulated by metabolic reprogramming. We previously demonstrated that compromised PGC1α signaling mediated ...

Department of Internal Medicine, Erasmus MC University Medical Centre Rotterdam, The Netherlands Correspondence to Dr L Hol, Department of Gastroenterology and Hepatology, Erasmus MC, University ...

Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium Correspondence to: Professor S Vermeire Department of Internal Medicine, Division of ...

Senescence is an autonomous state of cell cycle arrest which is an important mechanism preventing malignant transformation. Recent evidence suggests that cellular senescence may also have a ...

4 Department of Molecular Cell Biology and Electron Microscopy, Centre for Research Innovation, Support and Policy (CRISP), Maastricht University Medical Centre, Maastricht, The Netherlands ...