Emerging evidence highlights that epigenetic alterations—including DNA methylation, histone modification, and chromatin ...
New in vitro results show Telomir-1 adds KDM5 family inhibition to its previously reported KDM2/KDM6 and DNA methylation ...
Professor Alexander Hoffmann and Genhong Cheng from University of California, Los Angeles, jointly with Professor David ...
The outlook for the KAT6 inhibitors market is strengthening as interest in epigenetic targets grows and KAT6A/B gain ...
For the first time, Chinese scientists have fully revealed how a single plant somatic cell develops into a complete plant.
EZH2, the catalytic core of the Polycomb Repressive Complex 2 (PRC2), silences gene expression through H3K27me3 modification and is emerging as a master epigenetic regulator beyond cancer. The review ...
The transcription factor NF-κB is a key regulator of cell fate, extensively involved in various physiological and pathological processes such as ...
New in vitro results show Telomir-1 adds KDM5 family inhibition to its previously reported KDM2/KDM6 and DNA methylation activity, potentially representing a novel frontier in epigenetic therapy where ...
Chromatin remodelers play a pivotal role in gene regulation by shaping the physical structure of DNA around promoters and regulatory elements. While their biochemical activities are well studied, ...
The outlook for the KAT6 inhibitors market is strengthening as interest in epigenetic targets grows and KAT6A/B gain recognition as critical drivers of cancer progression. Although clinical ...
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